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Handbook of Her2-Targeted Agents in Breast Cancer

Handbook of Her2-Targeted Agents in Breast Cancer

Paperback

Medical Reference

ISBN10: 1907673938
ISBN13: 9781907673931
Publisher: Springer Pg
Published: Nov 3 2014
Pages: 96
Weight: 0.25
Height: 0.30 Width: 5.00 Depth: 7.80
Language: English
​Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15-25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.

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Medical Reference