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Handbook of Drug Metabolism

Handbook of Drug Metabolism

Paperback

Medical Reference

ISBN10: 0367399857
ISBN13: 9780367399856
Publisher: Crc Pr Inc
Published: Jun 19 2019
Pages: 612
Weight: 2.80
Height: 1.20 Width: 7.00 Depth: 9.90
Language: English
Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject in a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.

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Medical Reference