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Genetics, Development, and Evolution: 17th Stadler Genetics Symposium

Genetics, Development, and Evolution: 17th Stadler Genetics Symposium

Paperback

Series: Stadler Genetics Symposia

Medical ReferenceOther Animals

ISBN10: 1468451391
ISBN13: 9781468451399
Publisher: Springer Nature
Published: Dec 24 2012
Pages: 361
Weight: 1.32
Height: 0.78 Width: 6.69 Depth: 9.61
Language: English
One outstanding question in biology is the problem of devel- opment: how the genetic instructions encoded in the DNA become expressed in the morphological, physiological, and behavioral features of multicellular organisms, through an ordered sequence of events that extend from the first cell division of the zygote to the adult stage and eventual death. The problem is how a one- dimensional array of instructions is transformed into a four- dimensional entity, the organism that exists in space and time. Understanding this transformation is, nevertheless, necessary for mastering the process of evolution. One hundred and twenty-five years after The Origin of Species, we have gained some understanding of evolution at the genetic level. Genetic information is stored in the linear sequence of nucleotides in the DNA. Gene mutations, chromosomal reorganiza- tions, and a host of related processes introduce variation in the sequence and the amount of DNA. The fate of these variations is determined by interactions within the genome and with the outside environment that are largely understood. We have recently gained a glimpse of how the genome of eukaryotes is organized and will learn much more about it in the future, now that we have the research tools for it.

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