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Gene Function Analysis

Gene Function Analysis

Hardcover

Series: Methods in Molecular Biology, Book 1101

Medical ReferenceOther Animals

ISBN10: 1627037209
ISBN13: 9781627037204
Publisher: Springer Nature
Published: Nov 14 2013
Pages: 416
Weight: 2.12
Height: 0.94 Width: 7.00 Depth: 10.00
Language: English

The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds. In Gene Function Analysis, Second Edition, a number of computational and experimental techniques are presented for identifying not only the function of an individual gene, but also the partners that work with that gene. The theme of data integration runs strongly through the computational techniques, with many focusing on gathering data from different sources and different biomolecular types. Experimental techniques have evolved to determine function in specific tissues and at specific times during development. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

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