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Gene Delivery and Therapy for Neurological Disorders

Gene Delivery and Therapy for Neurological Disorders

Hardcover

Series: Neuromethods, Book 98

Medical Reference

ISBN10: 1493923056
ISBN13: 9781493923052
Publisher: Springer Nature
Published: Feb 4 2015
Pages: 359
Weight: 1.91
Height: 0.88 Width: 7.00 Depth: 10.00
Language: English

This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in the authors' laboratories. Although safe gene manipulation in neural cells can be achieved, it may still be years away from efficacious gene-based treatment of neurological disorders such as Parkinson's and Alzheimer's diseases due to the complexity of the underlying genetic/molecular mechanisms and the difficulty of developing reliable animal models. Gene Delivery and Therapy for Neurological Disorders seeks to aid researchers in this vital work. Written in the popular Neuromethods series format, chapters include the kind of detailed description and expert implementation advice that leads to success in the lab.

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