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GI Microbiota and Regulation of the Immune System

GI Microbiota and Regulation of the Immune System

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 635

Medical ReferenceBiology

ISBN10: 0387799893
ISBN13: 9780387799896
Publisher: Springer Nature
Published: Aug 21 2008
Pages: 149
Weight: 1.00
Height: 0.60 Width: 6.80 Depth: 10.10
Language: English
The idea that the microbial communities within the GI tract have a profound influence on general human health actually originated with Russian scientist Elie Metchnikov at the turn ofthe last century. Also known as the fatherofimmunol- ogy, Metchnikovbelievedthat putrefactivebacteriain the gut were responsible for enhancing the aging process. He theorized that ingestion ofhealthy bacteria found in fermented foods could counteract toxic bacteria and was the key to good health. His theories concerning good bacteria and health can be found in his treatise The ProlongationofLife: Optimistic Studies.Thesewritings promptedJapanesescientist Minoru Shirotatobegin investigationofhow fermentative bacteriaimprove health. He succeededin isolating astrainofLactobacillusthat could survive passage through the intestine, while promoting a healthy balance ofmicrobes. The Shirota strain is still used today in the fermented beverage Yakult.It is clear from a commercial standpoint that these ideas have inspired the development of a probiotic industry, which has expanded greatly in the U.S. over the past 5-10 years.

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