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Das Pankreaskarzinom: Frühdiagnostisches Und Therapeutisches Dilemma
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ISBN10: 3642705308
ISBN13: 9783642705304
Publisher: Springer Nature
Published: Dec 6 2011
Pages: 470
Weight: 1.70
Height: 0.98 Width: 6.69 Depth: 9.61
Language: German
ISBN13: 9783642705304
Publisher: Springer Nature
Published: Dec 6 2011
Pages: 470
Weight: 1.70
Height: 0.98 Width: 6.69 Depth: 9.61
Language: German
Seit der Erstbeschreibung des Pankreaskarzinoms durch Mondiere 1836 ist eine ständige Zunahme der Inzidenz des Pankreaskarzinoms zu verzeich- nen; heute ist es eines der häufigsten Malignome des Gastrointestinal- traktes mit etwa 6000 Neuerkrankungen pro Jahr in der Bundesrepublik Deutschland. Das onkologische Basiswissen über Entstehung, Wachstum sowie Ausbreitung ist sehr lückenhaft; es existiert für diesen Tumor bisher auch keine spezielle Screening-Methode und es fehlt ein Konzept zur Früh- diagnose. Der Stand der therapeutischen Möglichkeiten lä t sich an der Tatsache ablesen, da nur etwa 10% der Patienten im Tumorstadium I oder 11 diagnostiziert werden; eine Heilung ist bei weniger als 5% aller operierten Patienten zu erwarten. Mit diesem Buch über das Pankreaskarzinom, das ausgehend von Refe- raten eines Internationalen Symposions auf Schlo Reisensburg bei Ulm entstanden ist, verbindet sich die Hoffnung, in folgenden experimentellen und klinischen Problemen zu einheitlichen Standpunkten zu kommen: 1. Objektivierung von klinisch relevanten Tiermodellen des Pankreaskarzi- noms; 2. Neubewertung der Unterschiede in der pathologisch-anatomischen Klassifikation des Pankreaskarzinoms; 3. Neubewertung aller derzeit zur Diagnostik des Pankreaskarzinoms angewandten histologischen, serologi- schen und instrumentellen Diagnoseverfahren; 4. Definition von Therapie- gruppen und Neubewertung von chirurgischen Therapiemöglichkeiten mit Standardisierung der resezierenden Therapie. Die in dem Buch von anerkannten nationalen und internationalen Fachkollegen diskutierten Einzelaspekte aus dem Bereich der Onkologie und Pathologie sowie Diagnostik und Therapie, sollen dem interessierten Kli- niker die neuesten Ansatzpunkte bieten, um seinen Patienten mitPankreaskarzinom besser zu helfen.
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