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Multiple Sequenzalignments: Welches Programm Passt Zu Meinen Daten?
Paperback
Anatomy & PhysiologyBiologyBotany & Horticulture
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ISBN10: 3662588102
ISBN13: 9783662588109
Publisher: Springer Spektrum
Published: Jun 18 2019
Pages: 102
Weight: 0.39
Height: 0.25 Width: 6.14 Depth: 9.21
Language: German
ISBN13: 9783662588109
Publisher: Springer Spektrum
Published: Jun 18 2019
Pages: 102
Weight: 0.39
Height: 0.25 Width: 6.14 Depth: 9.21
Language: German
Dieses Buch ist ein praktischer Ratgeber für Biologinnen und Biologen, die Multiple Sequenzalignments (MSAs) für ihre Datenanalysen verwenden und einen verständlichen Überblick über die vielen verschiedenen Programme suchen. Trotz ihres wichtigen Stellenwertes in der Datenanalyse herrscht Unsicherheit unter den Forschenden wie MSA-Programme genau funktionieren - ganz zu schweigen davon, wie und warum die unterschiedlichen Analysen zu verschiedenen Ergebnissen führen. Welches Programm ist für die Auswertung meiner Daten das richtige und wie kann ich sicherstellen, alle relevanten Erkenntnisse aus den Alignments gezogen zu haben? Dieses Buch bietet hilfreiche Erklärungen und Hintergründe ohne gro e bioinformatische Vorkenntnisse vorauszusetzen und führt die Leserinnen und Leser langsam in die Thematik ein.Im ersten Teil des Buches werden die möglichen Einsatzfelder wie auch die Formate, die üblicherweise von MSA-Programmen produziert werden, im Detail beschrieben. Ebensowerden auf unkomplizierte Weise die zentralen Algorithmen sowie die inneren Abläufe der gängigsten MSA-Programme der Vergangenheit und der Gegenwart in grö erer Detailtiefe erklärt. Den zweiten Teil des Buches bildet ein ausführlicher datenbasierter Vergleich zwischen MSA-Programmen, der als Entscheidungshilfe für die Programmauswahl für dein nächstes Alignment dienen soll.
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