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Moderne Migränebehandlung: Molekulare Mechanismen, Neuromodulation und Präzisionsmedizin
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ISBN10: 3691737420
ISBN13: 9783691737424
Publisher: Bremen University Press
Published: Feb 13 2026
Pages: 110
Weight: 0.30
Height: 0.26 Width: 5.50 Depth: 8.50
Language: German
ISBN13: 9783691737424
Publisher: Bremen University Press
Published: Feb 13 2026
Pages: 110
Weight: 0.30
Height: 0.26 Width: 5.50 Depth: 8.50
Language: German
Migräne lässt sich heute besser kontrollieren als je zuvor. Doch ihr eigentliches Geheimnis liegt nicht in der Unterdrückung einzelner Symptome, sondern im Verständnis ihrer systemischen Dynamik. Migräne ist weit mehr als Kopfschmerz. Sie ist eine komplexe neurologische Systemerkrankung, die neuronale Netzwerke, vaskuläre Mechanismen, Immunprozesse und genetische Prädispositionen miteinander verbindet. Trotz jahrzehntelanger Forschung wurde sie lange missverstanden - als isoliertes Schmerzphänomen, als psychosomatische Reaktion oder als blo e Gefä erkrankung. Dieses Buch zeichnet die wissenschaftliche Transformation des Migräneverständnisses nach - von den frühen vaskulären Hypothesen über die Entdeckung des CGRP-Systems bis hin zu modernen Netzwerkmodellen des Gehirns. Es analysiert die Rolle der Cortical Spreading Depression, die Dynamik der Chronifizierung, Mechanismen zentraler Sensitivierung und die komplexe Interaktion zwischen Hirnstamm, Thalamus und Kortex. Ein besonderer Schwerpunkt liegt auf den therapeutischen Innovationen der letzten Jahre: CGRP-Antikörper, Gepants, Ditans, neuromodulatorische Verfahren sowie personalisierte Präventionsstrategien. Das Werk beleuchtet nicht nur Wirkmechanismen, sondern auch klinische Studien, regulatorische Entwicklungen und die Perspektiven einer zukünftigen Präzisionsmedizin. Dieses Buch zeigt, wie aus einer episodischen Störung ein chronisches Netzwerkphänomen werden kann - und wie moderne Medizin beginnt, diesen Prozess gezielt zu modulieren. Bremen University Press hat seit 2005 über 5.500 Fachbücher in verschiedenen Sprachen publiziert. Februar 2026
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