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Leishmaniose und die Rolle von Eisen
Paperback
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ISBN10: 6207904273
ISBN13: 9786207904273
Publisher: Verlag Unser Wissen
Published: Jul 31 2024
Pages: 60
Weight: 0.22
Height: 0.14 Width: 6.00 Depth: 9.00
Language: German
ISBN13: 9786207904273
Publisher: Verlag Unser Wissen
Published: Jul 31 2024
Pages: 60
Weight: 0.22
Height: 0.14 Width: 6.00 Depth: 9.00
Language: German
Die einzelligen kinetoplastiden protozoischen Parasiten der Gattung Leishmania sind die Erreger komplexer vernachlässigter Krankheiten, die als Leishmaniose bezeichnet werden, und stellen nach wie vor weltweit ein erhebliches Gesundheitsproblem dar. Kapitel 1 gibt einen kurzen Überblick über die Leishmaniose und skizziert die Anzahl der für die Behandlung verfügbaren Medikamente sowie die möglichen Angriffspunkte im Leishmania-Parasiten. Ziel von Kapitel 2 ist es, den aktuellen Wissensstand über den Erwerb und die Verwendung von Eisen durch Leishmania-Arten darzustellen. Für das Überleben und die Virulenz des Parasiten spielt Eisen als Metallion in vielen Bereichen des zellulären Stoffwechsels eine entscheidende Rolle als Kofaktor verschiedener Enzyme. Der Erwerb von Eisen ist für das Überleben der Parasiten unerlässlich. Da Eisen eine zentrale Rolle bei der Reaktion des Wirts und dem Parasitenstoffwechsel spielt, ist ein umfassendes Verständnis des Eisenstoffwechsels von Vorteil, um potenzielle therapeutische Möglichkeiten gegen Leishmaniose zu ermitteln.
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