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Genome Editing

Genome Editing

Paperback

BiologyZoology

ISBN10: 331981687X
ISBN13: 9783319816876
Publisher: Springer Nature
Published: Jun 12 2018
Pages: 166
Weight: 0.57
Height: 0.38 Width: 6.14 Depth: 9.21
Language: English
This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions.

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