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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Biophysics of voltage-activated sodium channels

Biophysics of voltage-activated sodium channels

de Oliveira Silva, Anita
de Moraes, Éder Ricardo

Paperback

Biology

ISBN10: 6208749662
ISBN13: 9786208749668
Publisher: Our Knowledge Publishing
Published: Mar 17 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Voltage-activated sodium channels form a superfamily of transmembrane proteins that act in electrical signalling and ion homeostasis in electrically excitable cells. Given their importance and diversity, it is essential that studies are continually carried out to clarify the pathological processes involving voltage-activated sodium channels and the pharmacology of their ligands. Due to their specificity in certain tissues at different stages of life, in-depth studies, both in vitro and in vivo, of these channels using experimental models that are closer to human reality should be encouraged. For this reason, it is important to correlate the understanding of pathophysiology and pharmacokinetics in order to obtain more efficient therapies. In the case of sodium channels that are specifically expressed in certain tissues, the side effects of the drug can be minimised. Therefore, the current lack of specific ligands for certain subtypes of sodium channels that are also specific makes this line of research as fascinating as it is promising.

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