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Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Hardcover

Medical Reference

ISBN10: 0387756124
ISBN13: 9780387756127
Publisher: Springer Nature
Published: Nov 24 2013
Pages: 466
Weight: 1.75
Height: 1.20 Width: 6.30 Depth: 9.20
Language: English

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development.

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