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Functional role of proteoglycans in prostate cancer

Functional role of proteoglycans in prostate cancer

Paperback

Medical Reference

ISBN10: 6202328657
ISBN13: 9786202328654
Publisher: Our Knowledge Publishing
Published: Jul 30 2025
Pages: 96
Weight: 0.31
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English
One of the main components of the extracellular matrix of human prostate tissue are proteoglycans (PGs) - complex protein-carbohydrate molecules consisting of crust protein and one or more carbohydrate chains of glycosaminoglycans (GAGs) attached to it. Proteoglycans are involved in cell-cell interactions with extracellular matrix proteins, growth factors, and chemokines and regulate the functional activity of cells. Through the interaction of crustal proteins proteoglycans and glycosaminoglycans with extracellular matrix molecules and signaling molecules, proteoglycans are involved in signal transduction between cells and the surrounding matrix, which affects motility, adhesion, growth and apoptosis and other cellular processes.

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Hodzhaeva, Naima

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Medical Reference