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Cytotoxicité
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ISBN10: 6200772541
ISBN13: 9786200772541
Publisher: Editions Notre Savoir
Published: Jul 28 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: French
ISBN13: 9786200772541
Publisher: Editions Notre Savoir
Published: Jul 28 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: French
Dans ce livre, nous pouvons observer les modifications au niveau moléculaire causées par les dommages causés par le HPV et les radiations du soleil, en particulier les radiations UV-B. Nous évaluerons deux protéines très importantes dans la croissance excessive des cellules, comme P53 et le facteur E2F1. Nous évaluerons deux protéines très importantes dans la croissance excessive des cellules, telles que P53 et le facteur E2F1, protéines d'une grande importance dans les processus cellulaires normaux comme dans le cancer. L'objectif est de parvenir à une synergie en termes de thérapie légèrement moins invasive et légèrement plus gratifiante, tout cela avec de faibles doses de rayonnement UV-B et des médicaments dérivés des fluoroquinolones. Tout cela dans un modèle expérimental avec des cellules dérivées du cancer HPV appelées cellules SiHa, qui portent l'un des HPV les plus cancérigènes, connu sous le nom de HPV-16. Parmi les plus cancérigènes, on trouve le HPV-13 et le HPV-18. Dans cette optique, des études ont été menées pour évaluer à quelle dose de rayonnement UV-B on peut obtenir un résultat favorable et non nocif. Il a été constaté que de faibles doses peuvent contribuer à la prolifération cellulaire avec un effet bien meilleur au niveau cellulaire.
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