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Bioinformatique translationnelle dans l'immunothérapie du cancer et le développement de vaccins
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ISBN10: 6630350227
ISBN13: 9786630350227
Publisher: Editions Notre Savoir
Pages: 136
Weight: 0.42
Height: 0.32 Width: 6.00 Depth: 9.00
Language: French
ISBN13: 9786630350227
Publisher: Editions Notre Savoir
Pages: 136
Weight: 0.42
Height: 0.32 Width: 6.00 Depth: 9.00
Language: French
Bioinformatique translationnelle dans l'immunothérapie du cancer et le développement de vaccins explore le rôle transformateur de la biologie computationnelle, de l'intelligence artificielle, de la génomique et de l'intégration des données multi-omiques pour faire progresser l'oncologie de précision. Il présente les approches bioinformatiques modernes permettant d'identifier des biomarqueurs tumoraux spécifiques, de prédire les réponses immunitaires, de découvrir des cibles thérapeutiques et de concevoir des vaccins anticancéreux de nouvelle génération. Il met en lumière la transposition de vastes ensembles de données biologiques en applications cliniques pertinentes, permettant ainsi des stratégies d'immunothérapie personnalisées et une amélioration du pronostic des patients. Les thèmes abordés incluent le profilage immunitaire, la prédiction des néoantigènes, l'apprentissage automatique pour la découverte de biomarqueurs, la biologie des systèmes, le séquençage unicellulaire, la pharmacogénomique et l'aide à la décision clinique. L'ouvrage examine également les technologies émergentes, les considérations éthiques, les défis réglementaires et les perspectives d'avenir de la recherche translationnelle en cancérologie. Il s'adresse aux chercheurs, cliniciens, doctorants et professionnels de la bioinformatique, de l'oncologie, de l'immunologie et de la biologie computationnelle.
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