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Epigenetics and Rare Diseases

Epigenetics and Rare Diseases

Hardcover

Series: Rare Diseases of the Immune System

Medical ReferenceGenetics

Currently unavailable to order

ISBN10: 3032029015
ISBN13: 9783032029010
Publisher: Springer
Published: Oct 17 2025
Pages: 274
Weight: 1.17
Height: 0.72 Width: 6.48 Depth: 9.36
Language: English
Epigenetics, as well as all -omics fields of study, such as transcriptomics, proteomics and metabolomics, have caused a revolution in all branches of medicine in recent years. This book provides a detailed evidence-based overview of the latest developments in how the recent acquisitions on the human genome and epigenome is relevant, and how it impacts our understanding of rare diseases of the immune system. The first part features the evolving thread from genetics to epigenetics, their molecular basis, endocrine disruptors, as well as chapters devoted to the fetal programming hypothesis and functional basis of neurodevelopment, and the placenta as originating element. Successive chapters include contributions on the impact of epigenetics on cancer, as well as a comprehensive array of disorders as autoimmune disorders, allergic and metabolic diseases, systemic vasculitis, aging and inflammatory diseases, neurological and psychiatric conditions. The overview closes with considerations on the -Omics revolution and precision medicine, and the reflection of epigenetics on the microbiome.

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Emmi, Lorenzo

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Medical Reference