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Epigenetic Methods in Neuroscience Research

Epigenetic Methods in Neuroscience Research

Hardcover

Series: Neuromethods, Book 105

Medical Reference

Currently unavailable to order

ISBN10: 1493927531
ISBN13: 9781493927531
Publisher: Springer Nature
Published: Oct 13 2015
Pages: 258
Weight: 1.87
Height: 0.81 Width: 7.28 Depth: 10.38
Language: English

This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system. Epigenetic Methods in Neuroscience Research guides readers through methods for the analyses of chromatin remodeling, transposable elements, non-coding RNAs, such as miRNAs, and circadian oscillations, including: analysis of DNA methylation in neuronal and glial cells or small tissue samples; sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry; affinity-based detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation; chromatin immunoprecipitation, or ChIP; miRNA high-throughput profiling and the in situ detection of miRNA subtle expression in the brain; analysis of genes with alternative 3'UTRs; and the cite-specific delivery of chromatin-modifying drugs. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.

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