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Essential Aspects of Immunometabolism in Health and Disease
Hardcover
ISBN13: 9783030866839
Publisher: Springer Nature
Published: Oct 22 2021
Pages: 278
Weight: 1.29
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases.
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