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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Endogenous Stem Cell-Based Brain Remodeling in Mammals

Endogenous Stem Cell-Based Brain Remodeling in Mammals

Junier, Marie-Pierre
Kernie, Steven G.

Paperback

Series: Stem Cell Biology and Regenerative Medicine

Medical ReferenceBiology

ISBN10: 1489978437
ISBN13: 9781489978431
Publisher: Springer Nature
Published: Aug 23 2016
Pages: 230
Weight: 0.75
Height: 0.51 Width: 6.14 Depth: 9.21
Language: English
This text highlights the endogenous regenerative potential of the central nervous system in neonates and juveniles and discusses possible ways it might be manipulated for medical purposes. The first section provides a descriptive summary of the salient steps of human brain development with a discussion of comparisons with other mammalian brains. It also provides a historical perspective on our understanding of ongoing brain development throughout the lifespan and serve to introduce the concept of brain plasticity following injury. The second part is devoted to the endogenous reparative potential of the brain, including its limitations, and articles focusing on defined pathologies (e.g. anoxia/hypoxia, epilepsy, traumatic brain injury and stress) in animal models and in humans pinpoint eventual ways these pathologies might be manipulated. The third and final focuses on the dark side of stem cells for brain repair or of the manipulation of spontaneous adaptive events after injury (e.g. genomic instability, sensitization to cancerous transformation and defective neural networks).

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