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Emerging Concepts of Tumor Exosome-Mediated Cell-Cell Communication

Emerging Concepts of Tumor Exosome-Mediated Cell-Cell Communication

Hardcover

Medical ReferenceBiologyChemistry

ISBN10: 1461436966
ISBN13: 9781461436966
Publisher: Springer Nature
Published: Sep 6 2012
Pages: 220
Weight: 1.27
Height: 0.70 Width: 6.20 Depth: 9.20
Language: English
In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.

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