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Drug Design and Discovery: Methods and Protocols
Hardcover
Series: Methods in Molecular Biology, Book 716
ISBN13: 9781617790119
Publisher: Humana
Published: Feb 16 2011
Pages: 69
Weight: 1.55
Height: 0.90 Width: 7.00 Depth: 10.00
Language: English
1. Virtual Screening for Lead Discovery
Yat T. Tang and Garland R. Marshall
2. Computer-Aided Drug Discovery and Development
Shuxing Zhang
3. Using Active Site Mapping and Receptor-Based Pharmacophore Tools: Prelude to Docking and De Novo/Fragment-Based Ligand Design
Ashutosh Tripathi, J. Andrew Surface, and Glen E. Kellogg
4. Methods for Evaluation of Structural and Biological Properties of Anti-Invasive Natural Products
Mudit Mudit, Mohammad Khanfar, Girish V. Shah, and Khalid A. El Sayed
5. Solid-Phase Peptide Synthesis Using Microwave Irradiation
Justin K. Murray, Jennifer Aral, and Les P. Miranda
6. Fluorescent and Lanthanide Labeling for Ligand Screens, Assays, and Imaging
Jatinder S. Josan, Channa R. De Silva, Byunghee Yoo, Ronald M. Lynch, Mark D. Pagel, Josef Vagner, and Victor J. Hruby
7. DNA-Directed Assembly Microarray for Protein and Small Molecule Inhibitor Screening
Ng Jin Kiat, Fritz Simeon, Too Heng Phon, and Parayil Kumaran Ajikumar
8. Selection of Peptide Ligands for Human Placental Transcytosis Systems Using In vitro Phage Display
Saleem Basha, Shruthi Vaidhyanathan, and Giovanni M. Pauletti
9. Optimization of the Tetrazolium Dye (MTT) Colorimetric Assay for Cellular Growth and Viability
Paul W. Sylvester
10. Imaging NF- κB Signaling in Mice for Screening Anti-Cancer Drugs
Delira Robbins and Yunfeng Zhao
11. Evaluation of Anticancer Agents Using Flow Cytometry Analysis of Cancer Stem Cells
Vineet Gupta, Qian-Jin Zhang, and Yong-Yu Liu
12. Chemical Screening with Zebrafish Embryos
Hanbing Zhong and Shuo Lin
13. iTRAQTM Labeling Coupled with LC-MALDI Mass Spectrometry for Monitoring Temporal Response of Colorectal Cancer Cells to Butyrate Treatment
Hwee Tong Tan, Teck Kwang Lim, Maxey C.M. Chung, and Qingsong Lin
14. Heterotypic Cell Adhesion Assay for the Study of Cell Adhesion Inhibition
Seetharama D. Satyanarayanajois, Sharon Ronald, and Jining Liu
15. Evaluation of Antibacterial Activity of Proteins and Peptides Using a Specific Animal Model for Wound Healing
Ramar Perumal Samy, Maung Maung Thwin, Vincent T.K.Chow, Ho Bow, and Ponnampalam Gopalakrishnakone
16. In vitro Immunogenicity Risk Assessment of Therapeutic Proteins in Preclinical Setting
Puneet Gaitonde and Sathy V. Balu-Iyer
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