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Drugs Targeting B-Cells in Autoimmune Diseases
Hardcover
Series: Milestones in Drug Therapy
ISBN13: 9783034807050
Publisher: Springer
Published: Dec 9 2013
Pages: 292
Weight: 1.40
Height: 0.90 Width: 6.30 Depth: 9.20
Language: English
Historic outline of the development of drugs targeting B-cells.- Understanding B-cell biology.- Pharmacological effects and mechanisms of action of agents blocking B cells.- Systemic lupus erythematosus: direct B-cell blocking.- Systemic lupus erythematosus: indirect B-cell blocking.- B-cell targeted therapies in rheumatoid arthritis.- B-cell targeted therapies in Primary Sjögren Syndrome.- Targeting B cells in ANCA-associated vasculitis.- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies.- B-cell targeted therapies in cryoglobulinemia.- B-cell targeted therapies in autoimmune cytopenias and thrombosis.- Targeting B cells in neurological autoimmune diseases.- Targeting B cells in other systemic autoimmune diseases.- Safety of B-cell targeted therapies.- The future potential of biosimilars targeting B-cells.
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