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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
DNA Replication: The Regulatory Mechanisms

DNA Replication: The Regulatory Mechanisms

Hughes, Patrick
Fanning, Ellen
Kohiyama, Masamichi

Paperback

BiologyChemistry

ISBN10: 364276990X
ISBN13: 9783642769900
Publisher: Springer Nature
Published: Dec 27 2011
Pages: 422
Weight: 1.37
Height: 0.91 Width: 6.14 Depth: 9.21
Language: English
DNA replication is a key event in the cell cycle. Although our knowledge is far from complete and many elusive regulatory mechanisms still remain beyondour grasp, many enzymes and a multiplicity of biochemical mechanisms involved have been discovered. Recent findings in E. coli have confirmed and yet surpassed the original hypothesis of F. Jacob. In yeast and higher eucaryotes, the apparent redundancy in putative origins and initiators has made an estimation of the importance of each identified element difficult to access. In spite of well established methodologies - which are also described in the book - the origin identification in mammalian chromosomes is still a controversial subject. On the other hand, considerable advances have been made in our understanding of virus DNA replication and this continues to deepen and broaden our understanding of the controls of cellular DNA replication.

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