Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
DNA Repair in Cancer Therapy

DNA Repair in Cancer Therapy

Panasci, Lawrence C.
Alaoui-Jamali, Moulay A.

Paperback

Series: Cancer Drug Discovery & Development

Medical Reference

ISBN10: 1617374806
ISBN13: 9781617374807
Publisher: Springer Nature
Published: Nov 19 2010
Pages: 363
Weight: 1.21
Height: 0.84 Width: 6.00 Depth: 9.00
Language: English
A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark relapse or drug resistance phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.

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