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Death Receptors and Cognate Ligands in Cancer

Death Receptors and Cognate Ligands in Cancer

Paperback

Series: Results and Problems in Cell Differentiation, Book 49

Medical ReferenceChemistry

ISBN10: 3642260764
ISBN13: 9783642260766
Publisher: Springer
Published: Mar 14 2012
Pages: 280
Weight: 0.92
Height: 0.62 Width: 6.14 Depth: 9.21
Language: English

Death receptors play a central role in directing apoptosis in mammalian cells. This process of active cell death is important for a number of biological processes, e.g. for the regulation of the immune system. Death receptors are cell surface receptors that transmit apoptotic signals initiated by corresponding death ligands. Many complex signaling pathways are activated and apoptosis is the final result of a complex biochemical cascade of events.

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Kalthoff, Holger

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