Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
D-Dopachrome Tautomerase (D-DT)

D-Dopachrome Tautomerase (D-DT)

Schulte Wibke Karin

Paperback

Medical Reference

Currently unavailable to order

ISBN10: 3838131614
ISBN13: 9783838131610
Publisher: S Dwestdeutscher Verlag F R Ho
Published: Feb 23 2012
Pages: 100
Weight: 0.35
Height: 0.24 Width: 6.00 Depth: 9.00
Language: English
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a pivotal regulator of the immune response implicated in the pathogenesis of various acute and chronic inflammatory diseases. In 1993, D-dopachrome tautomerase (D-DT) was discovered during an investigation of melanogenesis. The tertiary structure of D-DT is remarkably similar to MIF, identifying D-DT as the only known eukaryotic MIF homologue discovered to date. Despite D-DT's intriguing similarities to the very well studied MIF, there have been very few reports on the biological functions and mechanisms of action of D-DT. This dissertation aimed at the functional characterization of D-DT in biological and pathophysiologic conditions.

Also in

Medical Reference

View All