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Cyclic Peptide Design

Cyclic Peptide Design

Hardcover

Series: Methods in Molecular Biology, Book 2001

Medical ReferenceBiologyChemistry

ISBN10: 1493995030
ISBN13: 9781493995035
Publisher: Humana Pr
Published: May 28 2019
Pages: 332
Weight: 1.73
Height: 0.93 Width: 7.00 Depth: 10.00
Language: English
This book covers strategies to improve cell permeability, intestinal permeability, and metabolic stability, which are the typical liabilities associated with cyclic peptides, to enhance protein-protein recognition, and to build upon nature's cyclic peptides and macrocycles. Chapters also cover key peptide screening and display strategies, as well as important synthetic approaches towards cyclic and helical peptides. Cyclic peptides have become of significant importance as chemical tools in biology and drug discovery, since this class of chemicals has become a credible alternative source of new drug leads on par with traditional small molecules. As a part of the Methods in Molecular Biology series, this collection includes the kind of detail and implementation advice to aid researchers in the field.

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