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Conditional Mutagenesis: An Approach to Disease Models
Paperback
Series: Handbook of Experimental Pharmacology, Book 178
ISBN13: 9783642071218
Publisher: Springer Nature
Published: Nov 19 2010
Pages: 532
Weight: 1.70
Height: 1.20 Width: 6.10 Depth: 9.00
Language: English
Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.
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