Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models

Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models

Sarmento, Bruno

Hardcover

Medical ReferenceBiology

ISBN10: 0081000944
ISBN13: 9780081000946
Publisher: Woodhead Publishing
Published: Oct 9 2015
Pages: 408
Weight: 2.20
Height: 1.00 Width: 6.10 Depth: 9.10
Language: English

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

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