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Circadian Pharmacokinetics

Circadian Pharmacokinetics

Paperback

Medical Reference

ISBN10: 9811588090
ISBN13: 9789811588099
Publisher: Springer
Published: Oct 29 2021
Pages: 253
Weight: 0.82
Height: 0.55 Width: 6.14 Depth: 9.21
Language: English
This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.

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Wu, Baojian

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Medical Reference