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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Cell Immortalization

Cell Immortalization

Macieira-Coelho, Alvaro

Hardcover

Series: Progress in Molecular and Subcellular Biology, Book 24

Medical ReferenceBiology

ISBN10: 3540656189
ISBN13: 9783540656180
Publisher: Springer Nature
Published: Sep 17 1999
Pages: 208
Weight: 1.07
Height: 0.56 Width: 6.14 Depth: 9.21
Language: English
The problem of the long-term proliferation of cells is a seminal one. It has always been a hot subject in biology, a source of far-reaching hypotheses, even more so now when explanations for the mechanisms of cell prolifera- tive mortality or immortality seem within our reach. A question which is still debated is whether an infinite division potential can be a normal trait or is always the result of modifications leading to abnormal cell growth and escape from homeostasis. In general, investigators have been advocates of one of the two extremes, universal limited or unlim- ited normal proliferative potential. Since the long-term proliferative potential of cells concerns regulation of development, regeneration of tissues, and homeostatic control of cell growth, in brief survival of living organisms, and since the regulation of these processes is so different along the evolutionary scale, it is not surpris- ing that there does not seem to be any universal trait. The question of whether cells are endowed with finite or infinite prolifera- tive phenotypes has to be seen using the perspective of comparative biology.

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