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Cell Adhesion: Volume 16

Cell Adhesion: Volume 16

Hardcover

Series: Advances in Molecular and Cell Biology, Book 16

Biology

ISBN10: 0762301430
ISBN13: 9780762301430
Publisher: Elsevier Science
Published: Feb 24 1997
Pages: 235
Weight: 1.16
Height: 0.63 Width: 6.14 Depth: 9.21
Language: English

One prerequisite for the evolution of multicellular organisms was the invention of mechanisms by which cells could adhere to one another. At some point in our history, dividing cells no longer went their separate protozoic ways in the primordial oceans, but instead found that by maintaining an association, by sticking together but not fusing, numerous evolutionary advantages became possible. The subsequent development of specialized tissues and organs depended on the elaboration of incredibly sophisticated, regulatable cell-to-cell adhesion mechanisms which are known to operate in biological processes as diverse as the growth of the embryo, the immune response, the establishment of connections between nerve cells, and arteriosclerosis, to name just a few. Although we can only guess at the ancestral mechanisms that fostered the first primitive intercellular unions, some one billion years ago, we now recognize contemporary molecular themes with presumably ancient origins that mediate cell-cell interactions.

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Biology