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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Cancer Susceptibility: Methods and Protocols

Cancer Susceptibility: Methods and Protocols

Webb, Michelle

Paperback

Series: Methods in Molecular Biology, Book 653

Medical ReferenceGenetics

Currently unavailable to order

ISBN10: 1493957600
ISBN13: 9781493957606
Publisher: Humana
Published: Aug 23 2016
Pages: 295
Weight: 1.18
Height: 0.65 Width: 7.01 Depth: 10.00
Language: English
Part I: Identifying Cancer Susceptibility Genes 1. The Identification of Colon Cancer Susceptibility Genes by Using Genome-Wide Scans Denise Daley 2. Prioritizing Candidate Genetic Modifiers of BRCA1 and BRCA2 Using a Combinatorial Analysis of Global Expression and Polymorphism Association Studies of Breast Cancer Logan C. Walker and Amanda B. Spurdle 3. Microarray Based Comparative Genomic Hybridization (Array-CGH) as a Useful Tool for Identifying Genes Involved in Glioblastoma (GBM) Yolanda Ruano, Manuela Mollejo, Angel Rodríguez de Lope, José Luis Hernández-Moneo, Pedro Martínez, and Bárbara Meléndez 4. Multiplex Amplifiable Probe Hybridization (MAPH) Methodology as an Alternative to Comparative Genomic Hybridization (CGH) Ludmila Kousoulidou, Carolina Sismani, and Philippos C. Patsalis 5. Utilizing Saccharomyces cerevisiae to Identify Aneuploidy and Cancer Susceptibility Genes Erin D. Strome and Sharon E. Plon 6. Computational Identification of Cancer Susceptibility Loci Marko Laakso, Sirkku Karinen, Rainer Lehtonen, and Sampsa Hautaniemi 7. Digital Candidate Gene Approach (DigiCGA) for Identification of Cancer Genes Meng-Jin Zhu, Xiang Li, and Shu-Hong Zhao Part II: Screening Cancer Susceptibility Genes 8. The Use of Denaturing High Perfomance Liquid Chromatography (DHPLC) For Mutation Scanning of Hereditary Cancer Genes Deborah J. Marsh PhD and Viive M. Howell 9. Enhanced Mismatch Mutation Analysis: Simultaneous Detection of Point Mutations and Large Scale Rearrangements by Capillary Electrophoresis, Application to BRCA1 and BRCA2 Claude Houdayer, Virginie Moncoutier, Jérôme Champ, Jérémie Weber, Jean-Louis Viovy, and Dominique Stoppa-Lyonnet 10. Economical Protocol for Combined Single-Strand Conformation Polymorphism and Heteroduplex Analysis on a Standard Capillary Electrophoresis Apparatus Piotr Kozlowski and Wlodzimierz J. Krzyzosiak 11. Mutational Screening of hMLH1 and hMSH2 that Confer Inherited Colorectal Cancer Susceptibility Using Denature Gradient Gel Electrophoresis (DGGE) Tao Liu 12. s-RT-MELT: A Novel Technology for Mutation Screening Jin Li and G. Mike Makrigiorgos 13. Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer Susceptibility Genes Johan Staaf and Åke Borg 14. Development of a Scoring System to Screen for BRCA1/2 Mutations Gareth R. Evans and Fiona Lalloo 15. Use of Splicing Reporter Minigene Assay to Evaluate the Effect on Splicing of Unclassified Genetic Variants Pascaline Gaildrat, Audrey Killian, Alexandra Martins, Isabelle Tournier, Thierry Frébourg, and Mario Tosi 16. Functional Analysis of Human BRCA2 Variants Using a Mouse Embryonic Stem Cell-Based Assay Sergey G. Kuznetsov, Suhwan Chang, and Shyam K. Sharan 17. Developing Functional Assays for BRCA1 Unclassified Variants Michelle Webb

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