Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Coxiella Burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

Coxiella Burnetii: Recent Advances and New Perspectives in Research of the Q Fever Bacterium

Samuel, James E.
Toman, Rudolf
Heinzen, Robert A.

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 984

Medical ReferenceBiologyGeneral Computers

ISBN10: 9400743149
ISBN13: 9789400743144
Publisher: Springer Nature
Published: Jun 22 2012
Pages: 406
Weight: 1.60
Height: 1.10 Width: 6.40 Depth: 9.20
Language: English
Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools.

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