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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

Comparative Neuropathology of Chronic Experimental Allergic Encephalomyelitis and Multiple Sclerosis

Lassmann, H.

Paperback

Series: Schriftenreihe Neurologie Neurology, Book 25

Medical Reference

ISBN10: 3642455603
ISBN13: 9783642455605
Publisher: Springer Nature
Published: Aug 23 2014
Pages: 138
Weight: 0.56
Height: 0.33 Width: 6.69 Depth: 9.61
Language: English
For several decades the unsolved etiogenetic and therapeutic problems of multiple sclerosis have offered the strongest challenge to research in neu- rology. The hope of decisive theoretical and practical progress increased when an experimental model presenting far-reaching conformity of structural and pathogenetic features was developed, namely chronic re- lapsing experimental allergic encephalomyelitis (CREAE). During the past years, Dr. Lassmann has contributed substantially to the adaptation of this model with the aim of comprehensive evaluation, thoroughly fol- lowing up his own ideas in numerous studies of individual aspects. The new possibility of continuous and detailed investigation of the clinical, morphological and immunological characteristics of temporal phase sequence of autoimmune demyelination has led to many new findings, corrections offormer hypotheses, and, from correlated studies of human multiple sclerosis, a series of important data concerning, for example, early manifestations of demyelination, the range of so-called acute mul- tiple sclerosis and the incidence of remyelination. Moreover, Dr. Lass- mann has analysed several special problems which became definable in the course of his own studies or in collaboration with other groups, in- cluding the initial distribution of demyelinated foci, the cerebrospinal fluid phenomena and immunological findings in the nervous tissue. The results of these separate studies also led to a deeper understanding of demyelinating processes. This monograph integrates these studies and summarizes their re- sults.

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