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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
The CNS Control of Glucose Metabolism

The CNS Control of Glucose Metabolism

Grote, E. H.

Paperback

Series: ACTA Neurochirurgica Supplement, Book 31

Medical Reference

ISBN10: 3211816194
ISBN13: 9783211816196
Publisher: Springer Nature
Published: Jun 17 1981
Pages: 160
Weight: 0.52
Height: 0.37 Width: 6.00 Depth: 9.00
Language: English
In the clinic at Giessen during the last few years there has been an extensive programme of research into the various aspects of lesions of the diencephalon and brain stem and the associated autonomic and metabolic disturbances. As a continuation of this research programme Ernst Grote has investigated the central neuronal and hormonal factors acting on the peripheral regulation of glucose metabolism and their diverse inter-relationships. This research was made possible not only by the availability of well-documented clinical and experi- mental material with primary and secondary lesions of the hypo- thalamus and brain stem, but also by the advances in clinical endo- crinology and the development of radio-immuno-assays. By continuous systematic investigation of the basic values and their reaction to stress-tests, as well as to trauma and operation, he has elucidated the basic facts of the central and peripheral mechanisms which are concerned in the regulation of glucose, and also their disturbances. Of particular significance are his descriptions and interpretations of the characteristic hypothalamic syndromes, as combinations of hyperglycaemia, hyperinsulinaemia and hyperglucagonaemia; dif- ferent syndromes are produced by lesions at various levels of the brain stem and in central brain death. From this starting point it was possible to develop a rational treatment of this hormonal dys- regulation by means of somatostatin.

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