Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
A Clinical Perspective: EGFR Mutation Analysis in Primary Lung Cancers

A Clinical Perspective: EGFR Mutation Analysis in Primary Lung Cancers

Mahmud, Talha

Paperback

Medical Reference

ISBN10: 6208425158
ISBN13: 9786208425159
Publisher: LAP Lambert Academic Publishing
Published: Feb 13 2025
Pages: 160
Weight: 0.49
Height: 0.37 Width: 6.00 Depth: 9.00
Language: English
Lung cancer, or bronchogenic carcinoma, includes malignancies originating in the airways or lung parenchyma. Key risk factors are tobacco smoking, advancing age, COPD, and exposure to carcinogens like asbestos and radon. Additionally, genetic susceptibility plays a role, with 10-15% of never-smokers developing lung cancer, often linked to a strong family history. Advances in molecular pathogenesis have shown lung cancer to be a heterogeneous disease, driven by diverse molecular abnormalities. Tumor progression is influenced by receptors like Epidermal Growth Factor Receptors (EGFR), regulated by tyrosine kinases. Targeted therapies against these mutations are now first-line treatments, while chemotherapy is used for those who fail molecular therapies. This book explores demographic and clinical factors linked to mutant TK EGFR positivity in patients with advanced-stage (IV) lung cancer, based on research from a tertiary interventional pulmonology center in Pakistan.

Also from

Mahmud, Talha

View All

Also in

Medical Reference

View All