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Chronic septic granulomatosis in children

Chronic septic granulomatosis in children

Paperback

Medical Reference

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ISBN10: 6207492765
ISBN13: 9786207492763
Publisher: Our Knowledge Publishing
Published: Apr 29 2024
Pages: 56
Weight: 0.21
Height: 0.13 Width: 6.00 Depth: 9.00
Language: English
Chronic septic granulomatosis is a rare genetic immune deficiency resulting from dysfunction of the nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) complex in phagocytic cells.Clinical manifestations fall into two broad categories: infectious and inflammatory. Infections are the most common manifestations of the disease at any age, while inflammatory conditions are usually confined to adults.This is a serious disease. Management is mainly based on hygienic-dietary measures and chemo-prophylaxis to prevent fungal and bacterial infections.Life expectancy has improved markedly, but the prognosis may be jeopardized by infectious and inflammatory complications.

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