Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Chemical Carcinogenesis: Models and Mechanisms

Chemical Carcinogenesis: Models and Mechanisms

Feo, Francisco
Pani, Paolo

Paperback

Medical ReferenceBiology

ISBN10: 1475796420
ISBN13: 9781475796421
Publisher: Springer Nature
Published: Jul 18 2013
Pages: 679
Weight: 2.62
Height: 1.39 Width: 7.00 Depth: 10.00
Language: English
About two centuries after the communication by Sir Percival Pott that the chimney sweeper disease was a cancer and its suggestion that active compounds of soot were the causative agents, and about one century after the description of urinary bladder cancer in dye workers, an enormous number of substances have been synthesized and have probably come into contact with man. Research in cancer prevention is of primary importance, and may receive continuous support from new discoveries on cancer etiology and pathogenesis. If one accepts the multistage model of chemical carcinogenesis, one has also to accept that many events occur between the contact of carcino- genic compounds and their specific targets and the development of a clinically recognizable neoplasm. Thus, animal studies become essential to elucidate the different steps by which chemical carcinogens induce neoplasia. The analysis of these steps and the comparative evaluation of experimental models is essential to an understanding of pathogenesis.

Also in

Medical Reference

View All