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Cell-Mediated Effects of Immunoglobulins

Cell-Mediated Effects of Immunoglobulins

Hardcover

Series: Molecular Biology Intelligence Unit

Medical ReferenceBiology

ISBN10: 0412118211
ISBN13: 9780412118210
Publisher: Springer
Published: Dec 15 1996
Pages: 201
Weight: 1.29
Height: 0.50 Width: 7.00 Depth: 10.00
Language: English
Interaction of antigen-antibody complexes with cells via specific immunoglobulin Fc receptors (FcR) triggers major immunological reactions such as efficient uptake of antigen, phagocytosis of microorganisms, cytotoxicity towards tumor or virus infected cells, mast cell degranulation and inflammation, etc. This book reviews the FcR for the different immunoglobulin isotypes, focusing on the structural bases of their biological functions, and on the regulation of their expression in physiology and pathology.

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