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Cell Injury: Mechanisms, Responses, and Therapeutics, Volume 1066

Cell Injury: Mechanisms, Responses, and Therapeutics, Volume 1066

Paperback

Series: Annals of the New York Academy of Science, Book 1066

Medical ReferenceBiology

ISBN10: 1573316172
ISBN13: 9781573316170
Publisher: Wiley-Blackwell
Published: Mar 24 2006
Pages: 340
Weight: 1.00
Height: 0.71 Width: 6.00 Depth: 9.00
Language: English
When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance cell survival or remove irreparably injured cells. Following injury, cells attempt to seal breaks in their membranes, chaperone removal or refolding of altered proteins, repair damaged DNA, or if necessary commit to programmed cell death.

When cell injury is too extensive to permit reparative responses, acute cellular necrosis or apoptosis can result. Understanding injury at the subcellular organelle and molecular levels is essential for development of new therapeutic strategies and for optimal management of injured victims.

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