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Botulinum Neurotoxins

Botulinum Neurotoxins

Hardcover

Series: Current Topics in Microbiology and Immmunology, Book 364

Medical ReferenceCognition

ISBN10: 3642335691
ISBN13: 9783642335693
Publisher: Springer
Published: Dec 14 2012
Pages: 324
Weight: 1.30
Height: 1.00 Width: 6.30 Depth: 9.20
Language: English
The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.

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Rummel, Andreas

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Medical Reference