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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Biodegradable in Situ Microparticles for Sustained Protein Delivery

Biodegradable in Situ Microparticles for Sustained Protein Delivery

Körber, Martin

Paperback

Medical Reference

ISBN10: 3639076591
ISBN13: 9783639076592
Publisher: Blues Kids Of Amer
Published: Aug 22 2008
Pages: 332
Weight: 0.98
Height: 0.69 Width: 6.00 Depth: 9.00
Language: English
The objective of this work was to evaluate the suitability of in situ forming biodegradable microparticles for the controlled delivery of proteins. Particular goals were: a) to evaluate the flexibility of the release patterns of in situ implant and in situ microparticle formulations using hen egg white lysozyme as model protein; b) to characterize, if and how the integrity of the model protein is affected by formulation ingredients, the manufacturing process, sto-rage of the ISM and the release from the formulations; c) to optimize protein delivery from in situ forming implant and microparticle systems, with regard to shape and completeness of the release; d) to find / validate reliable methods allowing to extract and thus to characterize the model protein in biodegradable in situ formulations.

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