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Bioanalytical Estimation of Imiquimod in Rabbit Plasma by Rp-HPLC

Bioanalytical Estimation of Imiquimod in Rabbit Plasma by Rp-HPLC

Paperback

Medical Reference

ISBN10: 6206145808
ISBN13: 9786206145806
Publisher: Lap Lambert Academic Pub
Published: Feb 17 2023
Pages: 84
Weight: 0.30
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and showing various pharmacokinetic and pharmacodynamic parameters.

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