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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Bone: A Regulator of Physiology

Bone: A Regulator of Physiology

Scadden, David
Karsenty, Gerard

Hardcover

Series: Perspectives Cshl

Medical ReferenceAnatomy & PhysiologyBiology

Currently unavailable to order

ISBN10: 1621822206
ISBN13: 9781621822202
Publisher: Cold Spring Harbor Laboratory Press
Published: May 31 2018
Pages: 232
Weight: 1.45
Height: 0.70 Width: 7.10 Depth: 10.30
Language: English
Bone plays far more than just a structural role in our bodies. It actively communicates with our brains, kidneys, and other organs, releasing and responding to signaling molecules that regulate biological processes such as glucose metabolism and lymph node development. Defects in these interactions may lead to osteoporosis, multiple myeloma, and other diseases or developmental flaws.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines our current understanding of the dynamic interactions between bone and other organs and systems in the body and the molecules and mechanisms that mediate them. Contributors discuss endocrine factors that act on bone (e.g., parathyroid hormone and sex steroids) as well as molecules that are secreted by bone and act on other tissues (e.g., osteocalcin and FGF23). The interplay between bone and the nervous, immune, and vascular systems is explored, as is the influence of gut microbiota on bone homeostasis.

The authors also consider the diseases that result when homeostatic pathways are disrupted and how new knowledge of these pathways may be harnessed for the development of therapeutics. This volume is therefore a valuable reference for not only physiologists and endocrinologists but for all who are interested in diseases linked to the skeletal system.

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