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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids

Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids

Leeper, Finian J.
Croteau, R.
Vederas, John C.

Hardcover

Series: Topics in Current Chemistry, Book 209

Medical ReferenceChemistry

ISBN10: 3540665730
ISBN13: 9783540665731
Publisher: Springer
Published: Mar 27 2000
Pages: 247
Weight: 1.20
Height: 0.63 Width: 6.14 Depth: 9.21
Language: English
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.

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