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612-822-4611
Biofilm Associated Antimicrobial Resistance and Its Recovery

Biofilm Associated Antimicrobial Resistance and Its Recovery

Hardcover

Medical ReferenceBiology

ISBN10: 103225033X
ISBN13: 9781032250335
Publisher: CRC Press
Published: Dec 1 2023
Pages: 264
Weight: 1.55
Height: 0.69 Width: 7.00 Depth: 10.00
Language: English

A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of a microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance.

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