Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Aptamers in Biotechnology

Aptamers in Biotechnology

Lewis, Fleur

Hardcover

Biology

ISBN10: 1639897321
ISBN13: 9781639897322
Publisher: States Academic Pr
Published: Sep 19 2023
Pages: 244
Weight: 1.90
Height: 0.63 Width: 8.50 Depth: 11.00
Language: English
Aptamers are short sequences of artificial DNA or RNA that bind to specific target molecules such as peptides, proteins, carbohydrates, toxins, small molecules or live cells. In molecular biology, systematic evolution of ligands by exponential enrichment (SELEX) is a combinational chemistry technique used for generating oligonucleotides of either single-stranded DNA or RNA that specifically bind to a target ligand or ligands. Aptamers can be classified into two types, namely, peptide aptamers and DNA/RNA aptamers. There are several applications of aptamers, which can be categorized into therapeutic, diagnostic, reagent production, and engineering. Aptamers are suitable in diagnostic applications since they exhibit properties of tailored specificity and affinity, high thermal stability, and scalability of production. In therapeutics, aptamers can replace antibodies and facilitate the controlled release of therapeutic biomolecules such as growth factors. This book outlines the biotechnological applications of aptamers in detail. It aims to equip students and experts with the advanced topics and upcoming concepts in this area of study.

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