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Alternative Splicing and Disease
Hardcover
Series: Progress in Molecular and Subcellular Biology, Book 44
Medical ReferenceBiologyChemistry
ISBN13: 9783540344483
Publisher: Springer Nature
Published: Aug 3 2006
Pages: 257
Weight: 1.23
Height: 0.70 Width: 6.10 Depth: 9.20
Language: English
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medical implications, i.e. diseases, caused by alternative splicing. Alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences. The book also outlines possible targets for therapy.
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